Basic Information

Gene symbol STAT3 Synonyms ADMIO, ADMIO1, APRF, HIES Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description signal transducer and activator of transcription 3

Gene symbol TLR9 Synonyms CD289 Type of gene protein-coding
Gene perturbation-related omics dataset PertOrg
Description toll like receptor 9

GTO ID GTC2747
Trial ID NCT04995536
Disease Follicular Lymphoma | Diffuse Large B-Cell Lymphoma | B-Cell Non-Hodgkin's Lymphoma
Altered gene TLR9|STAT3
Therapeutic/Target gene Target gene
TherapysiRNA
Treatment CpG-STAT3 siRNA CAS3/SS3
Co-treatment Radiation Therapy
PhasePhase1
Recruitment statusRecruiting
TitleA Phase I Study of Intratumoral Injections of CpG-STAT3 siRNA (CAS3/SS3) in Combination With Local Radiation in Patients With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma (NHL)
Year2023
CountryUnited States
Company sponsorCity of Hope Medical Center
Other ID(s)20589|NCI-2021-06965|20589|P30CA033572|P50CA107399|Scopus Biopharma

Clinical Result

Cohort 1
Administration route intratumoral injection
Pts 18
Age Adult, Older_Adult

Relationship Graph

Overview of Knowledge Graph