Gene symbol | STAT3 | Synonyms | ADMIO, ADMIO1, APRF, HIES | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17q21.2 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | signal transducer and activator of transcription 3 |
Gene symbol | TLR9 | Synonyms | CD289 | Type of gene | protein-coding |
Chromosome | 3 | Map location | 3p21.2 | dbXrefs | |
Gene perturbation-related omics dataset | PertOrg | ||||
Description | toll like receptor 9 |
GTO ID | GTC2747 |
Trial ID | NCT04995536 |
Disease | Follicular Lymphoma | Diffuse Large B-Cell Lymphoma | B-Cell Non-Hodgkin's Lymphoma |
Altered gene | TLR9|STAT3 |
Therapeutic/Target gene | Target gene |
Therapy | siRNA |
Treatment | CpG-STAT3 siRNA CAS3/SS3 |
Co-treatment | Radiation Therapy |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | A Phase I Study of Intratumoral Injections of CpG-STAT3 siRNA (CAS3/SS3) in Combination With Local Radiation in Patients With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma (NHL) |
Year | 2023 |
Country | United States |
Company sponsor | City of Hope Medical Center |
Other ID(s) | 20589|NCI-2021-06965|20589|P30CA033572|P50CA107399|Scopus Biopharma |
Cohort 1 | |||||||
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