Basic Information

Gene symbol CD4 Synonyms CD4mut, IMD79, Leu-3, OKT4D, T4 Type of gene protein-coding
Description CD4 molecule

GTO ID GTC2735
Trial ID NCT04973527
Disease T-Cell Lymphoma | T-Cell Leukemia
Altered gene CD4
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment LCAR-T2C CAR-T cells
PhasePhase1
Recruitment statusTerminated
TitleLCAR-T2C CAR-T Cells in Relapsed or Refractory CD4+ T Lymphocyte Tumor
Year2021
CountryChina
Company sponsorBeijing Boren Hospital
Other ID(s)BRYY-IIT-LCYJ-2021-011

Clinical Result

Cohort 1
Administration route None
Dosage 5E5 cells/kg, 1.5E6 cells/kg, 5E6 cells/kg, 1E6 cells/kg
Donor type Autologous
Pts 9
Age Adult, Older_Adult
Lymph depletion Yes

Relationship Graph

Overview of Knowledge Graph