Basic Information

Gene symbol CA9 Synonyms CAIX, MN Type of gene protein-coding
Description carbonic anhydrase 9

GTO ID GTC2733
Trial ID NCT04969354
Disease Castration-Resistant Prostate Cancer
Altered gene CAIX
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CAIX CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitleClinical Study of CAIX-targeted CAR-T Cells in the Treatment of Advanced Renal Cell Carcinoma
Year2021
CountryChina
Company sponsorThe Affiliated Hospital of Xuzhou Medical University
Other ID(s)XYFY2021-KL092-02

Clinical Result

Cohort1: dose level 1
Administration route None
Dosage 1E7 cells/person
Pts 5
Age Adult, Older_Adult
Cohort2: dose level 2
Administration route None
Dosage 1E8 cells/person
Pts 5
Age Adult, Older_Adult
Cohort3: dose level 3
Administration route None
Dosage 1E9 cells/person
Pts 5
Age Adult, Older_Adult
Cohort4: dose level 4
Administration route None
Dosage 1E10 cells/person
Pts 5
Age Adult, Older_Adult

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