Basic Information

Gene symbol TNFRSF8 Synonyms CD30, D1S166E, Ki-1 Type of gene protein-coding
Description TNF receptor superfamily member 8

GTO ID GTC2728
Trial ID NCT04952584
Disease Hodgkin's Lymphoma | Nasal Type Extranodal NK/T-Cell Lymphoma
Altered gene CD30
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD30.CAR-EBVST
PhasePhase1
Recruitment statusNot Recruiting
TitleAllogeneic CD30 Chimeric Antigen Receptor Epstein-Barr Virus-Specific T Lymphocytes in Relapsed or Refractory CD30-Positive Lymphomas
Year2021
CountryUnited States
Company sponsorBaylor College of Medicine
Other ID(s)H-49736 TESTA

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E8 cells, 4E8 cells, 1E9 cells
Donor type Allogeneic
Pts 18
Age Child, Adult, Older_Adult

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