Basic Information

Gene symbol CD7 Synonyms GP40, LEU-9, TP41, Tp40 Type of gene protein-coding
Description CD7 molecule

GTO ID GTC2722
Trial ID NCT04938115
Disease T Cell Leukemia
Altered gene CD7
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD7 CAR-T cells
Generation2nd
Recruitment statusUnknown
TitleCell Therapy for CD7 Positive Acute Leukemia or Mixed Lineage Leukemia Except Those Who Are Diagnosed With T-ALL/T-LBL Using CD7-Specific CAR-T Cells
Year2021
CountryChina
Company sponsorHebei Senlang Biotechnology Inc., Ltd.
Other ID(s)CD7+ mixed lineage leukemia

Clinical Result

Cohort 1
Administration route None
Pts 5
Age Child, Adult, Older_Adult
Lymph depletion Yes
Outcome 4/5(CR/CRi)
Adverse reactions 5/5(CRS). None of the patients had neurotoxicity.
References DOI: 10.1182/blood-2021-146425

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