Gene symbol | WT1 | Synonyms | AWT1, GUD, NPHS4, WAGR, WIT-2, WT-1, WT33 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11p13 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | WT1 transcription factor |
GTO ID | GTC2705 |
Trial ID | NCT04911621 |
Disease | Brain Glioma |
Altered gene | WT1 |
Therapeutic/Target gene | Therapeutic gene |
Therapy | mRNA vaccine |
Treatment | DC Vaccine |
Co-treatment | temozolomide-based chemoradiation |
Phase | Phase1|Phase2 |
Recruitment status | Active, Not Recruiting |
Title | Adjuvant Dendritic Cell Immunotherapy Complementing Conventional Therapy for Pediatric Patients With High-grade Glioma and Diffuse Intrinsic Pontine Glioma |
Year | 2021 |
Country | Belgium |
Company sponsor | University Hospital, Antwerp |
Other ID(s) | CCRG19-002 |
Vector information | |||
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Cohort1: temozolomide-based chemoradiation | |||||
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Cohort2: conventional next-line treatment | |||||
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