Basic Information

Gene symbol WT1 Synonyms AWT1, GUD, NPHS4, WAGR, WIT-2, WT-1, WT33 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description WT1 transcription factor

GTO ID GTC2705
Trial ID NCT04911621
Disease Brain Glioma
Altered gene WT1
Therapeutic/Target gene Therapeutic gene
TherapymRNA vaccine
Treatment DC Vaccine
Co-treatment temozolomide-based chemoradiation
PhasePhase1|Phase2
Recruitment statusActive, Not Recruiting
TitleAdjuvant Dendritic Cell Immunotherapy Complementing Conventional Therapy for Pediatric Patients With High-grade Glioma and Diffuse Intrinsic Pontine Glioma
Year2021
CountryBelgium
Company sponsorUniversity Hospital, Antwerp
Other ID(s)CCRG19-002
Vector information
Vectordendritic cell

Clinical Result

Cohort1: temozolomide-based chemoradiation
Administration route intradermal injection
Age Child
Cohort2: conventional next-line treatment
Administration route intradermal injection
Age Child

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