Gene symbol | ERBB2 | Synonyms | CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2) | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17q12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | erb-b2 receptor tyrosine kinase 2 |
GTO ID | GTC2699 |
Trial ID | NCT04903080 |
Disease | Brain Ependymoma |
Altered gene | HER2 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | HER2 CAR-T cells |
Phase | Phase1 |
Recruitment status | Active, Not Recruiting |
Title | HER2-specific Chimeric Antigen Receptor (CAR) T Cells for Children With Ependymoma |
Year | 2021 |
Country | United States |
Company sponsor | Pediatric Brain Tumor Consortium |
Other ID(s) | PBTC-059 |
Cohort 1 | |||||||||
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