Gene symbol | CD276 | Synonyms | 4Ig-B7-H3, B7-H3, B7H3, B7RP-2 | Type of gene | protein-coding |
Chromosome | 15 | Map location | 15q24.1 | dbXrefs | |
Description | CD276 molecule |
GTO ID | GTC2696 |
Trial ID | NCT04897321 |
Disease | Rhabdomyosarcoma | Neuroblastoma | Germ Cell Cancer | Ewing Sarcoma | Carcinoma | Adrenocortical Carcinoma | Osteosarcoma | Rhabdoid Tumor | Hepatoblastoma | Desmoplastic Small Round Cell Tumor | Melanoma | Peripheral Nerve Sheath Neoplasm | Childhood Soft Tissue Sarcoma | Clear Cell Sarcoma | Wilms' Tumor |
Altered gene | CD276 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | B7-H3 CAR-T cells |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR) |
Year | 2021 |
Country | United States |
Company sponsor | St. Jude Children's Research Hospital |
Other ID(s) | 3CAR |
Cohort 1 | |||||||||||
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