Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC2682
Trial ID NCT04880434
Disease Mantle Cell Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment KTE-X19|Tecartus|Brexucabtagene autoleucel
Location approved US, EU, UK, Australia, Canada
Generation2nd
PhasePhase2
Recruitment statusActive, Not Recruiting
TitleStudy of Brexucabtagene Autoleucel (KTE-X19) in Participants With Relapsed/Refractory Mantle Cell Lymphoma (Cohort 3)
Year2021
CountryFrance|Germany|Netherlands|Spain|United Kingdom|United States
Company sponsorKite, A Gilead Company
Other ID(s)KTE-C19-102 (Cohort 3)|2015-005008-27
Vector information
Vectorlentivirus
ConstructscFv-CD28-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 2E6 cells/kg
Donor type Autologous
Pts 90
Age Adult, Older_Adult
Lymph depletion Yes

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