Gene symbol | NKX3-2 | Synonyms | BAPX1, NKX3.2, NKX3B, SMMD | Type of gene | protein-coding |
Chromosome | 4 | Map location | 4p15.33 | dbXrefs | |
Gene perturbation-related omics dataset | PertOrg | ||||
Description | NK3 homeobox 2 |
GTO ID | GTC2677 |
Trial ID | NCT04875754 |
Disease | Knee Osteoarthritis |
Altered gene | NKX3-2 |
Therapeutic/Target gene | Therapeutic gene |
Therapy | Gene transfer |
Treatment | ICM-203 |
Phase | Phase1|Phase2 |
Recruitment status | Recruiting |
Title | A Phase 1/2a, Double-Blind, Placebo-Controlled Single Dose Escalation Study of Intra-Articular ICM 203 in Subjects With Kellgren-Lawrence Grade 2 or Grade 3 Osteoarthritis of the Knee |
Year | 2021 |
Country | Australia |
Company sponsor | ICM Biotech Australia Pty Ltd. |
Other ID(s) | ICM 20-1001 |
Vector information | |||||||||
|
Cohort1: dose level 1 | |||||||||||
|
|||||||||||
Cohort2: dose level 2 | |||||||||||
|
|||||||||||
Cohort3: dose level 3 | |||||||||||
|