Basic Information

Gene symbol CD276 Synonyms 4Ig-B7-H3, B7-H3, B7H3, B7RP-2 Type of gene protein-coding
Description CD276 molecule

GTO ID GTC2676
Trial ID NCT04864821
Disease Osteosarcoma | Lung Cancer | Neuroblastoma | Stomach Cancer
Altered gene CD276
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment B7-H3 CAR-T cells
PhaseEarly_Phase1
Recruitment statusUnknown
TitleClinical Study of CD276 Targeted Autologous Chimeric Antigen Receptor T Cell Infusion in Patients With CD276 Positive Advanced Solid Tumor
Year2021
CountryChina
Company sponsorPersonGen BioTherapeutics (Suzhou) Co., Ltd.
Other ID(s)PA-P276-001

Clinical Result

Cohort 1
Administration route intravenous infusion|local tumor injection
Donor type Autologous
Pts 24
Age Child, Adult, Older_Adult

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