Basic Information

Gene symbol S Synonyms E2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description spike glycoprotein

GTO ID GTC2664
Trial ID NCT04847596
Disease Multiple Sclerosis
Altered gene S
Therapeutic/Target gene Therapeutic gene
TherapymRNA vaccine
Treatment COVID-19 mRNA Vaccine
Co-treatment Ofatumumab
Recruitment statusCompleted
TitleAn Open-label Multicenter Single-arm Pilot Study to Assess Immune Response to COVID-19 Vaccine in Participants With Relapsing Multiple Sclerosis Treated With Ofatumumab 20 mg Subcutaneously
Year2021
CountryUnited States|Puerto Rico
Company sponsorNovartis Pharmaceuticals
Other ID(s)COMB157GUS18

Clinical Result

Cohort 1
Administration route None
Dosage two doses
Pts 25
Age Adult
References PMID: 37769429

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