Gene symbol | CD274 | Synonyms | B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, hPD-L1 | Type of gene | protein-coding |
Chromosome | 9 | Map location | 9p24.1 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | CD274 molecule |
GTO ID | GTC2663 |
Trial ID | NCT04847466 |
Disease | Gastroesophageal Cancer | Head and Neck Squamous Cell Carcinoma |
Altered gene | PD-L1 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-NK cell |
Treatment | PD-L1 t-haNK |
Co-treatment | Pembrolizumab, N-803 |
Phase | Phase2 |
Recruitment status | Recruiting |
Title | Immunotherapy Combination: Irradiated PD-L1 CAR-NK Cells Plus Pembrolizumab Plus N-803 for Subjects With Recurrent/Metastatic Gastric or Head and Neck Cancer |
Year | 2021 |
Country | United States |
Company sponsor | National Cancer Institute (NCI) |
Other ID(s) | 10000096|000096-C |
Cohort 1 | |||||||||
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