Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC2658
Trial ID NCT04844086
Disease Non-Hodgkin's Lymphoma | Primary Mediastinal B-Cell Lymphoma | B-Cell Acute Lymphoblastic Leukemia | Follicular Lymphoma | Mantle Cell Lymphoma | Diffuse Large B-Cell Lymphoma | B-Cell Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment RPM CD19-mbIL15-CAR-T cells
PhasePhase1
Recruitment statusTerminated
TitleRPM CD19-mbIL15-CAR-T Cells in Patient With Advanced Lymphoid Malignancies
Year2021
CountryChina
Company sponsorEden BioCell Ltd.
Other ID(s)Eden 2020-01
Vector information
Vectorplasmid

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 2
Age Adult, Older_Adult
Lymph depletion Yes

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