Basic Information

Gene symbol CD33 Synonyms CD33rSiglec, SIGLEC-3, SIGLEC3, p67 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD33 molecule

GTO ID GTC2648
Trial ID NCT04835519
Disease Leukemia | Acute Myeloid Leukemia
Altered gene CD33
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD33 CAR-T cells
PhasePhase1|Phase2
Recruitment statusRecruiting
TitlePhase I/II Study of Enhanced CD33 CAR T Cells in Subjects With Relapsed or Refractory Acute Myeloid Leukemia
Year2021
CountryChina
Company sponsorBeijing Boren Hospital
Other ID(s)BRYY-IIT-LCYJ-2021-003

Clinical Result

Cohort 1
Administration route None
Dosage 5E5 cells/kg (±20%), 1E6 cells/kg (±20%)
Pts 25
Age Child, Adult, Older_Adult
Lymph depletion Yes

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