Basic Information

Gene symbol CD7 Synonyms GP40, LEU-9, TP41, Tp40 Type of gene protein-coding
Description CD7 molecule

GTO ID GTC2637
Trial ID NCT04823091
Disease T-Cell Non-Hodgkin's Lymphoma | T-Cell Chronic Lymphocytic Leukemia | T-Cell Lymphocytic Leukemia
Altered gene CD7
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD7 CAR-T cells
Generation2nd
PhasePhase1
Recruitment statusRecruiting
TitleAnti-CD7 CAR-Engineered T Cells for T Lymphoid Malignancies Malignancies
Year2021
CountryChina
Company sponsorWuhan Union Hospital, China
Other ID(s)CAR7-T-cells
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route None
Dosage 1E6~2E6 cells/kg (±20%)
Donor type Autologous|Allogeneic
Pts 24
Age Child, Adult, Older_Adult
Lymph depletion Yes

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