Basic Information

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC2632
Trial ID NCT04815356
Disease Hairy Cell Leukemia
Altered gene CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD22 CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitlePhase I Study of Anti-CD22 Chimeric Receptor T Cells in Patients With Relapsed/Refractory Hairy Cell Leukemia and Variant
Year2021
CountryUnited States
Company sponsorNational Cancer Institute (NCI)
Other ID(s)210019|21-C-0019

Clinical Result

Cohort 1
Administration route None
Dosage 1E5 cells/kg
Donor type Autologous
Pts 27
Age Adult, Older_Adult
Lymph depletion Yes

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