Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC2623
Trial ID NCT04796688
Disease Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | B-Cell Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment AT19
PhasePhase1
Recruitment statusRecruiting
TitleUniversal Chimeric Antigen Receptor-modified AT19 Cells for CD19+ Relapsed/Refractory Hematological Malignancies
Year2021
CountryChina
Company sponsorWuhan Union Hospital, China
Other ID(s)Universal AT19 cells

Clinical Result

Cohort 1
Administration route None
Dosage 0.5E7cells, 1E7cells, 2E7 cells
Donor type Autologous
Pts 27
Age Child, Adult, Older_Adult
Lymph depletion Yes

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