Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC2622
Trial ID NCT04796675
Disease Chronic Lymphocytic Leukemia | Acute Lymphoblastic Leukemia | Non-Hodgkin's Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment CD19 CAR-NK cells
PhasePhase1
Recruitment statusRecruiting
TitleCord Blood Derived Anti-CD19 CAR-Engineered NK Cells for B Lymphoid Malignancies
Year2021
CountryChina
Company sponsorWuhan Union Hospital, China
Other ID(s)CAR-NK-CD19 cells
Vector information
Vectorretrovirus

Clinical Result

Cohort 1
Administration route None
Dosage 0.01E7 cells/kg (±20%), 0.1E7 cells/kg (±20%), 1E7 cells/kg (±20%)
Pts 27
Age Adult, Older_Adult
Lymph depletion Yes

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