Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC2613
Trial ID NCT04787263
Disease Diffuse Large B-Cell Lymphoma | Acute Lymphoblastic Leukemia | Primary Mediastinal B-Cell Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
Generation2nd
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleCD19-CAR_Lenti T Cells in Pediatric Patients Affected by Relapsed/Refractory CD19+ ALL and DLBCL or PML
Year2021
CountryItaly
Company sponsorBambino Gesù Hospital and Research Institute
Other ID(s)CD19-CAR_Lenti

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1~3E6 cells/kg
Pts 32
Age Child, Adult
Lymph depletion Yes

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