Basic Information

Gene symbol MAGEA4 Synonyms CT1.4, MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B Type of gene protein-coding
Description MAGE family member A4

GTO ID GTC2595
Trial ID NCT04752358
Disease Esophagogastric Junction Cancer | Esophageal Cancer
Altered gene MAGE-A4
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment ADP-A2M4CD8
HLAHLA-A*02
PhasePhase2
Recruitment statusActive, Not Recruiting
TitleA Phase 2 Open-Label Clinical Trial of ADP-A2M4CD8 in Subjects With Advanced Esophageal or Esophagogastric Junction Cancers
Year2021
CountryUnited States
Company sponsorAdaptimmune
Other ID(s)ADP-0055-002
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route infusion
Dosage 0.1~1E10 cells
Donor type autologous
Age Adult, Older_Adult
Lymph depletion Yes

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