Basic Information


GTO ID GTC2590
Trial ID NCT04745403
Disease Hepatocellular Carcinoma
Altered gene HBV gene
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment HBV TCR-T cells
HLAHLA-A*02:01|HLA-A*24:02
PhasePhase1
Recruitment statusRecruiting
TitleSafety and Tolerability Study of Redirected HBV-Specific T Cells in Patients With Hepatitis B Virus (HBV)-Related Hepatocellular Carcinoma (SAFE-T-HBV)
Year2021
CountrySingapore
Company sponsorLion TCR Pte. Ltd.
Other ID(s)LTCR-HCC-3-3

Clinical Result

Cohort 1
Administration route infusion
Dosage 0.5~1E7 cells
Donor type autologous
Age Adult, Older_Adult
Lymph depletion No

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