Basic Information

Gene symbol MAGEC2 Synonyms CT10, HCA587, MAGEE1 Type of gene protein-coding
Description MAGE family member C2

GTO ID GTC2581
Trial ID NCT04729543
Disease Melanoma | Head and Neck Cancer
Altered gene MAGE-C2
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment MAGE-C2 TCR-T cells
HLAHLA-A*02:01
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleAdoptive Therapy With TCR Gene-engineered T Cells to Treat Patients With MAGE-C2-positive Melanoma and Head and Neck Cancer
Year2020
CountryNetherlands
Company sponsorErasmus Medical Center
Other ID(s)NL69011.000.19

Clinical Result

Cohort 1
Administration route infusion
Dosage 1~5E10 cells
Donor type autologous
Age Adult, Older_Adult
Lymph depletion No

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