Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC2572
Trial ID NCT04715217
Disease B-Cell Lymphoma
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD22 CAR-T cells
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleTargeting CD19 and CD22 CAR-T Cells Immunotherapy in Patients With Relapsed or Refractory B Cell Lymphoma
Year2021
CountryChina
Company sponsorShanxi Province Cancer Hospital
Other ID(s)CAR-T SXZL01

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 0.5E6 cells/kg, 2E6 cells/kg, 5E6 cells/kg
Donor type Autologous
Pts 24
Age Child, Adult, Older_Adult
Lymph depletion Yes

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