| Gene symbol | ERBB2 | Synonyms | CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2) | Type of gene | protein-coding |
| Chromosome | 17 | Map location | 17q12 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
| Description | erb-b2 receptor tyrosine kinase 2 | ||||
| Gene symbol | CD274 | Synonyms | B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, hPD-L1 | Type of gene | protein-coding |
| Chromosome | 9 | Map location | 9p24.1 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
| Description | CD274 molecule | ||||
| GTO ID | GTC2547 |
| Trial ID | NCT04684459 |
| Disease | Peritoneal Carcinoma | Malignant Pleural Effusion |
| Altered gene | HER2|PD-L1 |
| Therapeutic/Target gene | Target gene |
| Therapy | CAR-T cell |
| Treatment | HER2/PD-L1 CAR-T cells |
| Phase | Early_Phase1 |
| Recruitment status | Recruiting |
| Title | Dual-targeting HER2 and PD-L1 CAR-T for Cancers With Pleural or Peritoneal Metastasis |
| Year | 2020 |
| Country | China |
| Company sponsor | Sichuan University |
| Other ID(s) | MCART-002 |
| Cohort 1 | |||||||
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