Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

Gene symbol CSH1 Synonyms CS-1, CSA, CSMT, GHB3, PL, hCS-1, hCS-A Type of gene protein-coding
Description chorionic somatomammotropin hormone 1

GTO ID GTC2532
Trial ID NCT04662099
Disease Multiple Myeloma
Altered gene CS1|BCMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment BCMA/CS1 CAR-T cells
Generation2nd
PhasePhase1
Recruitment statusRecruiting
TitleT Cells Expressing a Bispecific CAR Targeting CS1 and BCMA in Relapsed/Refractory Multiple Myeloma
Year2020
CountryChina
Company sponsorWuhan Union Hospital, China
Other ID(s)CS1+BCMA bispecific CART

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 0.75~3E6 cells/kg
Pts 24
Age Adult, Older_Adult
Lymph depletion Yes

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