Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

Gene symbol TNFRSF13B Synonyms CD267, CVID, CVID2, IGAD2, RYZN, TACI, TNFRSF14B Type of gene protein-coding
Gene perturbation-related omics dataset PertOrg
Description TNF receptor superfamily member 13B

GTO ID GTC2526
Trial ID NCT04657861
Disease Multiple Myeloma
Altered gene BCMA|TACI
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment APRIL CAR-T cells
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleAPRIL CAR-T Cell Therapy for Patients With BCMA/TACI Positive Relapsed and/or Refractory Multiple Myeloma
Year2020
CountryChina
Company sponsorZhejiang University
Other ID(s)APRIL-001

Clinical Result

Cohort 1
Administration route intravenous infusion
Pts 36
Age Adult, Older_Adult
Lymph depletion Yes

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