Basic Information

Gene symbol ERBB2 Synonyms CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2) Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description erb-b2 receptor tyrosine kinase 2

GTO ID GTC2520
Trial ID NCT04650451
Disease HER2-Receptor Positive Breast Cancer
Altered gene HER2
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment BPX-603
PhasePhase1
Recruitment statusSuspended
TitleSafety and Activity Study of HER2-Targeted Dual Switch CAR-T Cells (BPX-603) in Subjects With HER2-Positive Solid Tumors
Year2020
CountryUnited States
Company sponsorBellicum Pharmaceuticals
Other ID(s)BPX603-201A

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 220
Age Adult, Older_Adult

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