Basic Information

Gene symbol CD276 Synonyms 4Ig-B7-H3, B7-H3, B7H3, B7RP-2 Type of gene protein-coding
Description CD276 molecule


Gene symbol FOLH1 Synonyms FGCP, FOLH, GCP2, GCPII, NAALAD1, PSM, PSMA, mGCP Type of gene protein-coding
Description folate hydrolase 1

GTO ID GTC2509
Trial ID NCT04637503
Disease Neuroblastoma
Altered gene GD2|PSMA|CD276
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment GD2/PSMA/B7-H3 T-cells
PhasePhase1|Phase2
Recruitment statusRecruiting
Title4SCAR-T Therapy Targeting GD2, PSMA and CD276 for Treating Neuroblastoma
Year2020
CountryChina
Company sponsorShenzhen Geno-Immune Medical Institute
Other ID(s)GIMI-IRB-20010

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E6~1E7 cells/kg
Pts 100
Age Child, Adult, Older_Adult

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