Basic Information

Gene symbol ALPP Synonyms ALP, IAP, ALPI, PALP, PLAP, PLAP-1 Type of gene protein-coding
Description alkaline phosphatase, placental

GTO ID GTC2504
Trial ID NCT04627740
Disease Endometrial Cancer | Ovarian Cancer
Altered gene ALPP
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment ALPP CAR-T cells
PhasePhase1|Phase2
Recruitment statusNot Recruiting
TitleAnti-ALPP CAR-T Cells Immunotherapy for Ovarian and Endometrial Cancer
Year2020
CountryChina
Company sponsorXinqiao Hospital of Chongqing
Other ID(s)TCRCureALPPCART
Vector information
Vectorretrovirus

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 20
Age Adult, Older_Adult
Lymph depletion Yes

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