Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC2502
Trial ID NCT04626765
Disease Childhood T-Cell Acute Lymphoblastic Leukemia
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD22 CAR-T cells
PhaseEarly_Phase1
Recruitment statusUnknown
TitleCAR-T for Children With Relapsed and Refractory Acute Lymphoblastic Leukemia
Year2020
CountryChina
Company sponsorHebei Senlang Biotechnology Inc., Ltd.
Other ID(s)CAR-T for Childhood B-ALL

Clinical Result

Cohort 1
Administration route None
Pts 50
Age Child, Adult
Lymph depletion Yes

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