Basic Information

Gene symbol KLRK1 Synonyms CD314, D12S2489E, KLR, NKG2-D, NKG2D Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description killer cell lectin like receptor K1

GTO ID GTC2498
Trial ID NCT04623944
Disease Myelodysplastic Syndrome | Acute Myeloid Leukemia
Altered gene NKG2D
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment NKE1
PhasePhase1
Recruitment statusRecruiting
TitleNKE1, Intravenous Allogeneic CAR NK Cells, in Adults With AML or MDS
Year2020
CountryUnited States
Company sponsorNkarta Inc.
Other ID(s)NKE1-101

Clinical Result

Cohort 1
Administration route None
Donor type Allogeneic
Pts 90
Age Adult, Older_Adult
Lymph depletion Yes

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