Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC2492
Trial ID NCT04608487
Disease Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment YesCAR-Ta|Axicabtagene Ciloleucel|axi-cel
Generation2nd
PhasePhase1
Recruitment statusActive, Not Recruiting
TitleAxi-cel in CNS Lymphoma
Year2020
CountryUnited States
Company sponsorDana-Farber Cancer Institute
Other ID(s)20-274
Vector information
Vectorlentivirus
ConstructscFv-CD28-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 18
Age Adult, Older_Adult
Lymph depletion Yes

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