Basic Information


GTO ID GTC2476
Trial ID NCT04577326
Disease Malignant Pleural Mesothelioma
Altered gene MESO
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment M28z1XXPD1DNR CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitleMesothelin-targeted CAR T-cell Therapy in Patients With Mesothelioma
Year2020
CountryUnited States
Company sponsorMemorial Sloan Kettering Cancer Center
Other ID(s)20-328
Vector information
Vectorretrovirus
Transgene/Inserted geneanti-ALPP CARs

Clinical Result

Cohort 1
Administration route None
Dosage 3E7 cells/kg
Donor type Autologous
Pts 30
Age Adult, Older_Adult

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