Basic Information

Gene symbol LAMP3 Synonyms CD208, DC LAMP, DC-LAMP, DCLAMP, LAMP, LAMP-3, TSC403 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description lysosomal associated membrane protein 3

Gene symbol UL83 Synonyms None Type of gene protein-coding
Description tegument protein pp65

GTO ID GTC2474
Trial ID NCT04573140
Disease Adult Glioblastoma
Altered gene UL83|LAMP
Therapeutic/Target gene Therapeutic gene
TherapymRNA vaccine
Treatment RNA-LP Vaccine
PhasePhase1
Recruitment statusRecruiting
TitleA Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)
Year2021
CountryUnited States
Company sponsorUniversity of Florida
Other ID(s)OCR32702-Adults|IRB202001710|R01FD007268-01A1
Vector information
Vectorliposome

Clinical Result

Cohort 1
Administration route intravenous injection
Dosage Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP liposome vaccine, dose escalation, BOIN design, ATD
Pts 28
Age Adult, Older_Adult
References PMID: 34101090

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