Gene symbol | S | Synonyms | E2 | Type of gene | protein-coding |
Chromosome | - | Map location | NC_004718.3 (21492..25259) | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | spike glycoprotein |
GTO ID | GTC2467 |
Trial ID | NCT04563702 |
Disease | COVID-19 |
Altered gene | S |
Therapeutic/Target gene | Therapeutic gene |
Therapy | dsRNA |
Treatment | VXA-CoV2-1 |
Phase | Phase1 |
Recruitment status | Completed |
Title | A Phase 1 Open-Label, Dose-Ranging Trial to Determine the Safety and Immunogenicity of an Adenoviral-Vector Based Vaccine (VXA-CoV2-1) Expressing a SARS-CoV-2 Antigen and dsRNA Adjuvant Administered Orally to Healthy Adult Volunteers VXA-CoV2-1.1-S Boost Substudy: Boost at 1 Year Post Initial Vaccination With an Adenoviral-Vector Based Vaccine VXA-CoV2-1.1-S Expressing a SARS-CoV-2 S Protein in a Subset of Subjects |
Year | 2020 |
Country | United States |
Company sponsor | Vaxart |
Other ID(s) | VXA-COV2-101 |
Vector information | |||||||
|
Cohort1: VXA-CoV2-1_dose level 1 | |||||||||
|
|||||||||
Cohort2: VXA-CoV2-1_dose level 2 | |||||||||
|