Basic Information

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

Gene symbol CD274 Synonyms B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, hPD-L1 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD274 molecule

GTO ID GTC2462
Trial ID NCT04556669
Disease Cervical Cancer | Sarcoma | Lung Non-Small Cell Carcinoma
Altered gene CD22|PDL1
Therapeutic/Target gene Target gene
TherapyCAR-T cell|CAR-TILs cell
Treatment SL22P CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitleAnti-PD-L1 Armored Anti-CD22 CAR-T/CAR-TILs Targeting Patients With Solid Tumors
Year2020
CountryChina
Company sponsorHebei Senlang Biotechnology Inc., Ltd.
Other ID(s)Senl_C22P CAR-T/CAR-TIL

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 30
Age Adult, Older_Adult

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