Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC2461
Trial ID NCT04556266
Disease Leukemia | Lymphoma | B-Cell Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
Generation2nd
PhasePhase1
Recruitment statusWithdrawn
TitleA Phase I Trial of Donor- Derived 19-28z CAR T Cells Following Allogeneic Transplant for the Treatment of CD19 Malignancies
Year2020
CountryUnited States
Company sponsorMemorial Sloan Kettering Cancer Center
Other ID(s)17-331

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E4 cells/kg, 1E5 cells/kg, 2E5 cells/kg, 4E5 cells/kg
Donor type Allogeneic
Pts 0
Age Adult

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