Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1

GTO ID GTC2458
Trial ID NCT04553393
Disease Refractory or Relapsed Aggressive R/R B-NHL with Huge Tumor Burden
Altered gene CD19|CD20
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD20 CAR-T cells
Co-treatment chidamidEdecitabine
PhasePhase1|Phase2
Recruitment statusUnknown
TitleDecitabine-primed Tandem CD19/CD20 CAR T Cells Plus Epigenetic Agents in Aggressive r/r B-NHL With Huge Tumor Burden
Year2020
CountryChina
Company sponsorChinese PLA General Hospital
Other ID(s)CHN-PLAGH-BT-060

Clinical Result

Cohort 1
Administration route None
Pts 80
Age Child, Adult, Older_Adult

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