Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | MS4A1 | Synonyms | B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11q12.2 | dbXrefs | |
Description | membrane spanning 4-domains A1 |
GTO ID | GTC2458 |
Trial ID | NCT04553393 |
Disease | Refractory or Relapsed Aggressive R/R B-NHL with Huge Tumor Burden |
Altered gene | CD19|CD20 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD19/CD20 CAR-T cells |
Co-treatment | chidamidEdecitabine |
Phase | Phase1|Phase2 |
Recruitment status | Unknown |
Title | Decitabine-primed Tandem CD19/CD20 CAR T Cells Plus Epigenetic Agents in Aggressive r/r B-NHL With Huge Tumor Burden |
Year | 2020 |
Country | China |
Company sponsor | Chinese PLA General Hospital |
Other ID(s) | CHN-PLAGH-BT-060 |
Cohort 1 | |||||||
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