Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

GTO ID GTC2446
Trial ID NCT04537442
Disease Multiple Myeloma
Altered gene BCMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment IM21 CAR-T cells
PhasePhase1
Recruitment statusUnknown
TitleClinical Study to Evaluate the Safety and Efficacy of IM21 CAR-T Cells in the Treatment of Elderly Patients With Relapsed or Refractory Multiple Myeloma
Year2020
CountryChina
Company sponsorBeijing Immunochina Medical Science & Technology Co., Ltd.
Other ID(s)Immunochina

Clinical Result

Cohort 1
Administration route None
Pts 16
Age Adult, Older_Adult
Outcome 7/16(CR); 9/16(PR)
Adverse reactions 9/16(thrombocytopenia); 11/16(neutropenia); 16/16(leukopenia); 11/16(lymphopenia); 5/16(anemia)
References DOI: 10.1182/blood-2022-166011

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