Gene symbol | CTAG1B | Synonyms | CTAG, ESO1, CT6.1, CTAG1, LAGE-2, LAGE2B, NY-ESO-1 | Type of gene | protein-coding |
Chromosome | X | Map location | Xq28 | dbXrefs | |
Description | cancer/testis antigen 1B |
GTO ID | GTC2435 |
Trial ID | NCT04526509 |
Disease | Lung Non-Small Cell Carcinoma | Synovial Sarcoma | Myxoid Liposarcoma |
Altered gene | NY-ESO-1 |
Therapeutic/Target gene | Target gene |
Therapy | TCR-T cell |
Treatment | GSK3901961 |
HLA | HLA-A*02:01 |
Phase | Phase1 |
Recruitment status | Active, Not Recruiting |
Title | Master Protocol to Assess the Safety and Recommended Phase 2 Dose of Next Generations of Autologous Enhanced NY-ESO-1/ LAGE-1a TCR Engineered T-cells, Alone or in Combination With Other Agents, in Participants With Advanced Tumors |
Year | 2020 |
Country | United States |
Company sponsor | GlaxoSmithKline |
Other ID(s) | 209012|2019-004446-14 |
Cohort1: GSK3901961_NSCLC | |||||||||
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Cohort2: GSK3901961_SS/MRCLS | |||||||||
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Cohort3: GSK3845097_SS/MRCLS | |||||||||
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Cohort4: GSK4427296_SS/MRCLS | |||||||||
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