Administration route |
None |
Dosage |
3E6 cells/kg, 6E6 cells/kg, 1E7 cells/kg |
Donor type |
Allogeneic |
Pts |
9 |
Age |
Child, Adult, Older_Adult |
Lymph depletion |
Yes |
Outcome |
9/9(CR at 28 dyas). The overall response rates (ORR) were 100% (9/9), 88.9% (8/9), and 75% (6/8) at 3 month, 6 month, and 12 month, respectively. The 1-year progression-free and overall survival were 77.8% and 85.7%, respectively. |
Adverse reactions |
Three patients had acute graft-versus-host-disease (grade I, n = 1; grade II, n = 1; grade IV, n = 1) and all resolved after treatment. |
References |
PMID:
38204488
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