Gene symbol | VEGFA | Synonyms | L-VEGF, MVCD1, VEGF, VPF | Type of gene | protein-coding |
Chromosome | 6 | Map location | 6p21.1 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | vascular endothelial growth factor A |
GTO ID | GTC2428 |
Trial ID | NCT04514653 |
Disease | Age-Related Macular Degeneration |
Altered gene | VEGFA |
Therapeutic/Target gene | Therapeutic gene |
Therapy | Gene transfer |
Treatment | RGX-314 |
Phase | Phase2 |
Recruitment status | Recruiting |
Title | A Phase 2, Randomized, Dose-escalation, Ranibizumab-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of RGX-314 Gene Therapy Delivered Via One or Two Suprachoroidal Space (SCS) Injections in Participants With Neovascular Age-Related Macular Degeneration (nAMD) (AAVIATE) |
Year | 2020 |
Country | United States |
Company sponsor | AbbVie |
Other ID(s) | RGX-314-2102 |
Vector information | |||||||||
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