Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
GTO ID | GTC2426 |
Trial ID | NCT04512716 |
Disease | Diffuse Large B-Cell Lymphoma | B-Cell Acute Lymphoblastic Leukemia | Diffuse Large B-Cell Lymphoma Activated B-Cell Type | Non-Hodgkin's Lymphoma | Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type |
Altered gene | CD19 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD19 CAR-T cells |
Generation | 2nd |
Phase | Early_Phase1 |
Recruitment status | Recruiting |
Title | Iomab-ACT: A Pilot Study of 131-I Apamistamab Followed by CD19-Targeted CAR T-Cell Therapy for Patients With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia or Diffuse Large B-Cell Lymphoma |
Year | 2020 |
Country | United States |
Company sponsor | Memorial Sloan Kettering Cancer Center |
Other ID(s) | 20-382 |
Cohort 1 | |||||||||
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