Basic Information

Gene symbol IL13RA2 Synonyms CD213A2, CT19, IL-13R, IL13BP Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description interleukin 13 receptor subunit alpha 2

GTO ID GTC2424
Trial ID NCT04510051
Disease Brain Neoplasm
Altered gene IL13RA2
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment IL13Ra2 CAR-T cells
Generation2nd
PhasePhase1
Recruitment statusRecruiting
TitleCAR T Cells After Lymphodepletion for the Treatment of IL13Rα2 Positive Recurrent or Refractory Brain Tumors in Children
Year2020
CountryUnited States
Company sponsorCity of Hope Medical Center
Other ID(s)19130|NCI-2020-05158|19130|P30CA033572

Clinical Result

Cohort 1
Administration route ventricular system infusion
Donor type Autologous
Pts 18
Age Child, Adult
Lymph depletion Yes
Adverse reactions no dose limiting toxicities (DLTs)
References PMID: 37961215

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