Basic Information

Gene symbol FOXP3 Synonyms AIID, DIETER, IPEX, JM2, PIDX, XPID Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description forkhead box P3

GTO ID GTC2420
Trial ID NCT04504669
Disease Clear Cell Renal Cell Carcinoma | Squamous Cell Carcinoma | Small Cell Lung Cancer | Triple-Receptor Negative Breast Cancer | Gastroesophageal Cancer | Lung Non-Small Cell Carcinoma | Melanoma | Cervical Cancer
Altered gene FOXP3
Therapeutic/Target gene Target gene
TherapyASO
Treatment AZD8701
PhasePhase1
Recruitment statusActive, Not Recruiting
TitleA Phase I First-in-Human Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Efficacy of AZD8701 Administered Intravenously as Monotherapy and in Combination With Durvaluamb (MEDI4736) in Participants With Advanced Solid Tumours.
Year2020
CountryCanada|France|Spain|United States
Company sponsorAstraZeneca
Other ID(s)D9950C00001|04504669|2019-004539-22
Vector information
VectorNo vector was used

Clinical Result

Cohort1: AZD8701
Administration route intravenous infusion
Age Adult, Older_Adult
Cohort2: AZD8701_Durvalumab
Administration route intravenous infusion
Age Adult, Older_Adult

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