Gene symbol | FOXP3 | Synonyms | AIID, DIETER, IPEX, JM2, PIDX, XPID | Type of gene | protein-coding |
Chromosome | X | Map location | Xp11.23 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | forkhead box P3 |
GTO ID | GTC2420 |
Trial ID | NCT04504669 |
Disease | Clear Cell Renal Cell Carcinoma | Squamous Cell Carcinoma | Small Cell Lung Cancer | Triple-Receptor Negative Breast Cancer | Gastroesophageal Cancer | Lung Non-Small Cell Carcinoma | Melanoma | Cervical Cancer |
Altered gene | FOXP3 |
Therapeutic/Target gene | Target gene |
Therapy | ASO |
Treatment | AZD8701 |
Phase | Phase1 |
Recruitment status | Active, Not Recruiting |
Title | A Phase I First-in-Human Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Efficacy of AZD8701 Administered Intravenously as Monotherapy and in Combination With Durvaluamb (MEDI4736) in Participants With Advanced Solid Tumours. |
Year | 2020 |
Country | Canada|France|Spain|United States |
Company sponsor | AstraZeneca |
Other ID(s) | D9950C00001|04504669|2019-004539-22 |
Vector information | |||
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Cohort1: AZD8701 | |||||
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Cohort2: AZD8701_Durvalumab | |||||
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