Basic Information

Gene symbol AFP Synonyms AFPD, FETA, HPAFP Type of gene protein-coding
Gene perturbation-related omics dataset PertOrg
Description alpha fetoprotein

GTO ID GTC2416
Trial ID NCT04502082
Disease Hepatocellular Carcinoma
Altered gene AFP
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment ET140203 TCR-T cells
HLAHLA-A*02
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleAn Open-Label, Dose Escalation, Multi-Center Phase I/II Research Trial to Assess the Safety of ET140203 T Cells and Determine the Recommended Phase II Dose (RP2D) in Adults With Advanced Hepatocellular Carcinoma (HCC) (ARYA-1)
Year2020
CountryUnited States
Company sponsorEureka Therapeutics Inc.
Other ID(s)ETUS19AFPAR121
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route None
Donor type autologous
Age Adult, Older_Adult
Lymph depletion No

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