Gene symbol | AFP | Synonyms | AFPD, FETA, HPAFP | Type of gene | protein-coding |
Chromosome | 4 | Map location | 4q13.3 | dbXrefs | |
Gene perturbation-related omics dataset | PertOrg | ||||
Description | alpha fetoprotein |
GTO ID | GTC2416 |
Trial ID | NCT04502082 |
Disease | Hepatocellular Carcinoma |
Altered gene | AFP |
Therapeutic/Target gene | Target gene |
Therapy | TCR-T cell |
Treatment | ET140203 TCR-T cells |
HLA | HLA-A*02 |
Phase | Phase1|Phase2 |
Recruitment status | Recruiting |
Title | An Open-Label, Dose Escalation, Multi-Center Phase I/II Research Trial to Assess the Safety of ET140203 T Cells and Determine the Recommended Phase II Dose (RP2D) in Adults With Advanced Hepatocellular Carcinoma (HCC) (ARYA-1) |
Year | 2020 |
Country | United States |
Company sponsor | Eureka Therapeutics Inc. |
Other ID(s) | ETUS19AFPAR121 |
Vector information | |||
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Cohort 1 | |||||||||
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