Basic Information

Gene symbol S Synonyms E2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description spike glycoprotein


GTO ID GTC2404
Trial ID NCT04480957
Gene therapy-related omics dataset GTD0320 | GTD0321 | GTD0322 | GTD0323 | GTD0324 | GTD0325 | GTD0326 | GTD0327 | GTD0328 | GTD0329 | GTD0330 | GTD0331 | GTD0332 | GTD0333 | GTD0334 | GTD0335 | GTD0336 | GTD0337 | GTD0338 | GTD0339 | GTD0340 | GTD0341 | GTD0342 | GTD0343 | GTD0344 | GTD0345
Disease COVID-19
Altered gene VEEV|S
Therapeutic/Target gene Therapeutic gene
TherapymRNA vaccine
Treatment ARCT-021
PhasePhase1|Phase2
Recruitment statusCompleted
TitleA Phase 1/2 Randomised, Double Blinded, Placebo Controlled, Ascending Dose Study to Assess the Safety, Tolerability, and Immunogenicity of ARCT-021 in Healthy Adult Subjects
Year2020
CountrySingapore
Company sponsorArcturus Therapeutics, Inc.
Other ID(s)ARCT-021-01
Vector information
Vectorlipid nanoparticle

Clinical Result

Cohort1: 21 - 55 years
Administration route intramuscular injection
Dosage ARCT-021, Escalation Cohort dose, 0.5 mL
Age Adult, Older_Adult
Cohort2: 56 - 80 years
Administration route intramuscular injection
Dosage ARCT-021, Expansion Cohort dose, 0.5 mL
Age Adult, Older_Adult

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