Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

GTO ID GTC2395
Trial ID NCT04452994
Disease Multiple Myeloma
Altered gene BCMA
Therapeutic/Target gene Target gene
TherapyCAR-DC cell|CAR-T cell
Treatment Carvykti|Ciltacabtagene Autoleucel|Cilta-cel|JNJ-68284528
Location approved US, EU, UK, Japan, Australia, Canada
Generation2nd
Recruitment statusNo Longer Available
TitleIndividual Patient Investigational New Drug (IND) Expanded Access Program of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy for Participant With Multiple Myeloma
Year2020
CountryUnited States
Company sponsorJanssen Research & Development, LLC
Other ID(s)CR108848
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Age Child, Adult, Older_Adult
Lymph depletion Yes

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