Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

GTO ID GTC2393
Trial ID NCT04447573
Disease Multiple Myeloma
Altered gene BCMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment BCMA CAR-T cells
Recruitment statusUnknown
TitleImmunotherapy With BCMA CAR-T Cells in Treating Patients With Relapsed or Refractory Multiple Myeloma
Year2020
CountryChina
Company sponsorHebei Senlang Biotechnology Inc., Ltd.
Other ID(s)BCMA CAR-T

Clinical Result

Cohort 1
Administration route None
Pts 21
Age Adult, Older_Adult
Lymph depletion Yes
Outcome 8/21(CR), 12/21(PR), 95%(ORR), at 1 month. 16/20(CR), 3/20(PR), 95%(ORR), at 3 month.
Adverse reactions 7/21(CRS); 1/21(neurotoxicity)
References DOI: 10.1182/blood-2023-185271

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